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Old Pals

Old Pals

Cognitive, immune & gut
complex for senior longevity.

Healthier poops. Shinier coat. Brighter eyes. 
Everything a senior dog needs for more good days.

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27B CFU, 10-strain probiotics + prebiotic
4 mushrooms for immune & allergy support
KSM-66® Ashwagandha for stress support
Lion's Mane + MCT Oil for cognitive health
By canine nutritionist with 11+ years experience
3rd-party tested
90-day money-back
Made in VT, USA 90-day money-back Delivers in 3-5 days

25 active ingredients (pre & probiotics, mushrooms, antioxidants, vitamins and minerals) working in synergy to support digestion, immunity, mental clarity, and overall wellness in senior dogs. 

Active Ingredients:

  • Bifidobacterium Longum
  • Lactobacillus Acidophilus
  • Bifidobacterium Animalis
  • Lactobacillus Plantarum
  • Enterococcus Faecium
  • Lactobacillus Rhamnosus
  • Bacillus Coagulans
  • Saccharomyces Boulardii
  • Bifidobacterium Bifidum
  • Lactobacillus Casei
  • Organic Reishi Extract (fruiting body)
  • Organic Lion’s Mane Extract (fruiting body)
  • Organic Turkey Tail Extract (fruiting body)
  • Organic Chaga Extract (sclerotium)
  • Organic Cordyceps Extract (fruiting body)
  • FOS (prebiotic fiber)
  • Acerola Cherry Extract (17% vitamin C)
  • MCT Oil (50% caprylic acid)
  • Organic Broccoli Sprout Powder
  • Milk Thistle Extract
  • KSM-66® Ashwagandha Root Extract
  • Decaffeinated Green Tea Extract (15% EGCG)
  • Japanese Knotweed (98% resveratrol)
  • Zinc (as picolinate)
  • VegD3® (vitamin D3)

Inactive Ingredients: Flaxseed

Small dogs (<25 lbs): 1 scoop a day
Medium dogs (25-50 lbs): 2 scoops a day
Large dogs (51-100 lbs): 3 scoops a day
Giant dogs (> 100 lbs): 4 scoops a day

Start with half the suggested amount and increase gradually to the recommended daily amount.

Old Pals is third-party tested for label accuracy, purity, and contaminants. See the full Certificate of Analysis below.

Lot V2500535 · Tested April 2026
Tap the image to view the full report.

View full details

THE SCIENCE BEHIND
SLOWING SENIOR DECLINE

THE SCIENCE
BEHIND SLOWING
SENIOR DECLINE

The biggest factor in a senior dog's quality of life is how well their brain, immune system and gut work together.

Tummy issues, allergy flare-ups, and more lethargy are unavoidable as our dogs get older.

But to slow the decline and give them more good days, we need to understand what’s actually happening in their bodies.

THE GUT loses diversity. Less of the good bacteria, more of the bad. Digestion gets worse, appetite drops, and poops become more inconsistent.

THE IMMUNE SYSTEM goes off-balance and starts overreacting to triggers it used to handle. That causes the recurring scratching, easier seasonal flares and the hot spots that keep coming back.

THE BRAIN slows down. An aging brain uses its fuel less efficiently, so cognition dulls and engagement fades. These are the days when they’re distant, lethargic and not themselves.

And these systems don’t decline on their own. 

The gut talks directly to the brain.
70% of the immune system lives in the gut.
Cognitive decline weakens immunity. 

As one system slows, the rest follow.
This is what 'aging' actually means.

That's why we built Old Pals - the first 25 ingredient senior formula that supports the gut, immune and brain together to slow the decline.

Everything that gives them
more good days, in 1 scoop.

WHAT'S INSIDE

25 clinically-researched ingredients
working together to slow senior decline.

WHAT'S INSIDE

25 clinically-researched ingredients
working together to slow senior decline.

Studied in dogs for its role in modulating inflammatory markers and supporting gut lining integrity. May help reduce gut sensitivity and promote immune balance.

Works With: FOS prebiotics to promote colonization and gut lining integrity.

Studied in dogs to support beneficial bacteria colonization, maintain healthy gut bacterial balance, and support normal immune function

Works With: Other probiotic strains including Bifidobacterium strains, S. boulardii and FOS prebiotics for comprehensive digestive support.

One of the most widely studied strains for dogs. Shown to support healthy stool consistency, ease digestive upset, and enhance gut immunity.

Works With: L. casei and FOS to reinforce microbial diversity and stool quality.

Shown in canine trials to reduce GI upset and support microbial diversity post-antibiotics or during dietary shifts.

Works With: S boulardii, L. acidophilus, L. Casei, B. Bifidum, E. Faecium to support digestive health and gut resilience.

Studied in dogs to support healthy gut bacterial balance and healthy stool quality when combined with other probiotic strains.

Works With: B. animalis, L. acidophilus, L. rhamnosus and prebiotics to support gut balance and digestive health.

Spore-forming strain that survives the harsh gastric environment. Studied in dogs for its role in promoting postbiotic activity and nutrient absorption.

Works With: FOS prebiotics to improve probiotic effectiveness.

Studied in dogs to support digestive health, beneficial gut bacteria, and a healthy immune response.

Works With: B. longum and B. bifidum to support healthy gut function.

A beneficial yeast studied in dogs for its role in supporting digestive health and microbial balance - especially during times of digestive stress like diet changes or antibiotic use.

Works With: FOS and Lactobacillus strains to reinforce gut recovery.

Strengthens the intestinal barrier which may prevent harmful bacteria and toxins from passing through the gut wall into the bloodstream.

Works With: Studied in combination with L. acidophilus for digestive support.

We use a patented strain originally isolated from healthy dogs. Studied for supporting digestive function, microbiome diversity, and stool quality in dogs.

Works With: L. plantarum, B. animalis and FOS prebiotics to support the gut and immune system.

Prebiotic fiber that feeds beneficial bacteria - working synergistically with key probiotic strains to support overall digestive health.

Works With: Supports the survival, colonization, and effectiveness of key probiotic strains including B. coagulans, S. boulardii, Lactobacillus and Bifidobacterium species.

One of nature's most powerful immune supporters. Rich in polysaccharopeptide (PSP), a beta-glucan compound that supports immune cell function. Studied in dogs to support immune cells and the body's natural defense mechanisms. 

Works With: Reishi for immune support.

An adaptogenic mushroom that provides beta-glucans and triterpenes to support balanced immune function and healthy inflammatory response.

Works With: Probiotics to support a healthy gut microbiome.

An adaptogenic mushroom rich in beta-glucans and polysaccharides that support stamina and immune function.

Works With: Ashwagandha for stress support and probiotics to support the gut barrier.

A potent natural source of beta-glucans and polyphenols with antioxidant properties. Studies in dogs support its role in helping maintain cellular health and immune function.

Works With: Reishi, Turkey Tail, Lion's Mane and Probiotics for cognitive, immune and gut support.

One of nature's richest sources of vitamin C with plant compounds (bioflavonoids) that absorb more effectively than synthetic vitamin C to support immune function and cellular health.

Works With: Vitamin D3 and Zinc to support healthy immune response.

Contains sulforaphane - a compound studied for its ability to activate liver detox enzymes. Studies in dogs have shown that sulforaphane is effectively absorbed and utilized, supporting their natural detoxification processes

Works With: Milk Thistle for liver and detox support.

Milk thistle seeds are rich in a group of antioxidants called silymarins, studied in dogs for their role in supporting healthy liver enzyme levels and antioxidant balance. Helps maintain normal liver health and protects against oxidative damage.

Works With: Organic Broccoli Sprout (sulforaphane) for liver and oxidative stress protection.

VegD3® is a plant-based vitamin D3 sourced from lichen. Unlike generic D3, VegD3® is cleaner, more sustainable, and free from animal byproducts. Studied in dogs to support healthy immune system function and balanced immune responses.

Works With: Zinc and Vitamin C for synergistic immune regulation.

Concentrated source of resveratrol - a potent antioxidant studied in dogs for it's cardiovascular and anti-inflammatory benefits.

Works With: EGCG from Decaffeinated Green Tea and Reishi for antioxidant support.

Provides EGCG (epigallocatechin gallate) - a powerful antioxidant compound that helps protect cells and support healthy inflammation response. Decaffeinated to be safe for dogs.

Works With: Japanese Knotweed and Reishi for for antioxidant support.

Essential trace mineral involved in skin, immune and cellular health. Studied in dogs to support T-cell activity and tissue repair.

Works With: Vitamin C and D3 for immune and skin barrier integrity.

Promotes nerve growth factor (NGF) production, supporting memory and cognitive sharpness. May also help promote a more balanced gut microbiome and support gut-brain axis function.

Works With: Reishi, Cordyceps, and Ashwagandha for cognitive, stress, and immune support.

Provides an efficient energy source called ketones, an alternative fuel that supports brain and heart energy metabolism. Studied in dogs to support cognitive function and healthy aging.

Works With: B vitamins to support overall cognitive function.

A potent adaptogen, KSM-66® is the most clinically studied form of ashwagandha with standardized potency. Studied in dogs to support calm behavior and manage stress naturally.

Works With: Reishi for stress support and probiotics for overall well-being.

  • Tag

    BETTER DIGESTION

    Poops and appetite get better first as the beneficial bacteria start working in your dog’s gut.

  • Tag

    HEALTHIER SKIN

    As the gut improves, the skin gets healthier and scratching starts to ease. Less gnawing at the paws, less restless itching.

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    MORE ALERT

    This is when parents usually notice something's different. Longer eye contact. More engaged. Some dogs may start playing more like they used to.

  • Tag

    NEW NORMAL

    This is now the new normal. Healthier. More present. More good days than bad.

ONE SMARTER FORMULA

ONE SMARTER FORMULA

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WHAT OTHERS LEAVE OUT
WHAT OTHERS
LEAVE OUT
Old Pals
Other Supplements (What you'll typically find in other brands)

27B CFU, 10 Probiotic Strains

1B - 5B CFU, 3-12 strains

5mg Zinc Picolinate

2mg - 4mg Zinc

1800mg Organic Fruiting-Body Mushrooms

(Chaga, Cordyceps, Reishi, Turkey Tail & Lion's Mane)

500mg - 1000mg total (lower quality mycelium)

300mg FOS Prebiotics

<100mg or none

50mg KSM-66® Ashwagandha Root Extract

Generic low-potency ashwagandha

100mg Milk Thistle Extract

Usually found only in liver support products

100mg Acerola Cherry Extract

(17% vitamin C)

Usually synthetic vitamin C

100mg MCT Oil

(50% caprylic acid)

Rarely included

100mg Organic Broccoli Sprout Powder

Rarely included

50 IU VegD3®

(vitamin D3)

Rarely included

40mg Japanese Knotweed Extract

(98% resveratrol)

Rarely included

30mg Decaffeinated Green Tea Extract

Rarely included

GOOD DAYS GUARANTEE

GOOD DAYS GUARANTEE

Most supplement guarantees give you 30 days. That's barely enough time for the ingredients to build up in your dog's system for real changes.

That’s why we offer a 90-day money-back guarantee instead. Because real improvements in their quality of life take consistency - and you deserve to see that process happen, risk-free.

If you don't see noticeable improvements within 90 days, we'll refund every cent.
No return needed.

SHOP OLD PALS

GUT – BRAIN

GUT – BRAIN

Ever notice your senior dog get more agitated when their stomach's not feeling great? That's not a coincidence. Their gut has more nerve cells than their spinal cord and it talks directly to their brain. Fix the gut and calm behavior follows.

GUT – IMMUNE

GUT – IMMUNE

70% of your dog's immune system lives in their gut. When digestion is off, immunity drops. When immunity is weak, the gut struggles. Old Pals supports both at once.

BRAIN – IMMUNE

BRAIN – IMMUNE

Chronic stress weakens immunity. A calmer dog is a healthier dog - and reduced inflammation protects brain tissue from age-related decline.

NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE
NASC CERTIFIED
COMPLEMENTS FRESH DIETS
MADE IN USA
3RD PARTY TESTED
90-DAY GUARANTEE

THE GOOD STUFF

THE GOOD STUFF

10 Probiotic Strains

10 Probiotic Strains

10 researched probiotic strains that support healthy gut flora, digestion and stool quality.
FOS Prebiotics

FOS Prebiotics

Prebiotic fiber that works synergistically with key probiotic strains to support overall digestive health.
KSM-66® Ashwagandha

KSM-66® Ashwagandha

A potent adaptogen studied in dogs to support calm behavior and manage stress naturally.
MCT Oil

MCT Oil

Provides an efficient energy source called ketones, an alternative fuel that supports brain and heart energy metabolism.
Lion's Mane

Lion's Mane

Promotes nerve growth factor (NGF) production, supporting memory and cognitive sharpness.
Reishi

Reishi

An adaptogenic mushroom that supports balanced immune function and healthy inflammatory response.
Turkey Tail

Turkey Tail

Studied in dogs to support immune cells and the body's natural defense mechanisms.
Chaga

Chaga

A potent natural source of beta-glucans and polyphenols to support cellular health and immune function.
Cordyceps

Cordyceps

An adaptogenic mushroom rich in beta-glucans and polysaccharides that support stamina and immune function.
Milk Thistle

Milk Thistle

Contains antioxidants called silymarins studied in dogs for their role in supporting liver and cellular health.
Broccoli Sprout

Broccoli Sprout

Contains sulforaphane - a compound studied for its ability to support natural detox processes.
Acerola Cherry

Acerola Cherry

One of nature's richest sources of vitamin C to support immune function and cellular health.
Green Tea

Green Tea

An antioxidant that helps protect cells and supports a healthy inflammation response. Decaffeinated to be safe for dogs.
Japanese Knotweed

Japanese Knotweed

Concentrated source of resveratrol - a potent antioxidant studied in dogs for it's cardiovascular and anti-inflammatory benefits.
  • ABOUT OLD PALS
  • PRODUCT & INGREDIENTS

What does Old Pals support?

Old Pals is designed to support the areas that matter most as dogs age: gut health, immune balance, and cognitive function. It's a blend of probiotics, fruiting-body mushrooms, antioxidants, and vitamins and minerals that help maintain comfort and vitality in senior dogs.

Every dog is different but many pet parents notice early signs like digestive improvements (firmer stools, less gas) within 1-2 weeks. Behavioral changes (calmer demeanor, better engagement) can take up to 4 weeks. Immune and cognitive benefits develop over 8-12 weeks. We're supporting natural processes, not masking symptoms, so sustainable improvements take time.

Old Pals is formulated with senior dogs in mind, but it's safe for adult dogs too. Puppies under 12 months should only use it under the guidance of a veterinarian to ensure it meets their developmental needs.

We recommend checking with your veterinarian before adding any new supplement if your dog is taking medication or has an existing medical condition. Because Old Pals contains prebiotic fibers, it may delay the absorption of drugs taken at the same time. Old Pals can generally be given alongside most medications, but timing matters for probiotics. If your dog is on antibiotics, giving Old Pals about 2 hours apart may help maintain probiotic activity. For steroids or other long-term medications, your veterinarian can help you decide the best timing and routine for your dog.

What ingredients are in Old Pals and why were they chosen?

Old Pals uses ingredients with a purpose: clinically studied ingredients such as the use of 10 individual probiotic strains (instead of a blend), real fruiting-body mushrooms, and ingredients such as milk thistle, and organic broccoli sprout for liver support, as well as antioxidants to support healthy aging.

Yes, they can consume certain mushrooms when they are the right species and properly prepared. Old Pals uses fruiting-body extracts from well-studied varieties like Reishi, Lion’s Mane, Turkey Tail, Cordyceps, and Chaga. These mushrooms are known for immune and cellular support and are suitable for daily use. If your dog is taking medications that affect immune function, check with your veterinarian before adding mushroom-based supplements.

These ingredients offer gentle daily support for dogs, especially seniors. Acerola Cherry provides natural vitamin C to help maintain cellular health and overall vitality. Milk Thistle is widely used for its supportive role in normal liver function. Organic Broccoli Sprout is a source of sulforaphane that provides antioxidant support. Together, they offer extra support to help keep your dog feeling good as they grow older.

More good days for your
senior, or your money back.